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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HLTF
All Species:
17.27
Human Site:
S821
Identified Species:
29.23
UniProt:
Q14527
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14527
NP_003062.2
1009
113929
S821
P
E
E
L
A
R
D
S
E
K
K
S
D
M
E
Chimpanzee
Pan troglodytes
XP_001138277
1009
113822
S821
P
E
E
L
A
R
D
S
E
K
K
S
D
M
E
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_534300
1106
124184
T918
P
E
E
L
A
C
D
T
E
K
K
S
N
T
E
Cat
Felis silvestris
Mouse
Mus musculus
Q6PCN7
1003
113298
S815
P
E
E
L
A
C
D
S
D
K
E
S
S
M
E
Rat
Rattus norvegicus
NP_001099948
974
110023
S786
P
E
E
L
A
C
D
S
D
N
K
S
D
M
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508504
884
99044
P725
I
D
L
R
K
K
N
P
Q
T
K
S
L
I
V
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001090145
999
112576
I811
Q
E
D
L
D
S
S
I
N
K
K
P
D
Q
K
Zebra Danio
Brachydanio rerio
XP_693071
942
104740
T756
Y
P
G
E
Q
A
E
T
R
S
D
T
G
E
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P34739
1061
118357
R878
A
S
K
N
L
L
K
R
S
N
P
V
F
N
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786706
1093
121576
E900
P
K
D
R
S
D
T
E
N
D
D
T
D
R
E
Poplar Tree
Populus trichocarpa
XP_002308876
799
88908
E640
L
L
I
A
S
R
V
E
N
P
A
R
K
S
V
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FF61
881
98598
E722
L
L
M
A
S
R
Q
E
N
P
N
T
K
S
V
Baker's Yeast
Sacchar. cerevisiae
P31244
790
91412
L631
L
V
E
E
L
Y
K
L
R
S
N
K
R
T
I
Red Bread Mold
Neurospora crassa
Q7S1P9
1222
137173
I1038
G
A
S
P
E
P
R
I
S
L
Q
R
V
G
A
Conservation
Percent
Protein Identity:
100
99.5
N.A.
85.5
N.A.
83.6
81.4
N.A.
71.7
N.A.
64.3
53.1
N.A.
21.1
N.A.
N.A.
34.5
Protein Similarity:
100
99.8
N.A.
88
N.A.
89.7
87.9
N.A.
78.5
N.A.
79.3
69.8
N.A.
41.2
N.A.
N.A.
53.1
P-Site Identity:
100
100
N.A.
73.3
N.A.
73.3
80
N.A.
13.3
N.A.
33.3
0
N.A.
0
N.A.
N.A.
20
P-Site Similarity:
100
100
N.A.
86.6
N.A.
86.6
86.6
N.A.
46.6
N.A.
46.6
20
N.A.
6.6
N.A.
N.A.
46.6
Percent
Protein Identity:
33.6
N.A.
N.A.
36
22.7
25.2
Protein Similarity:
50.4
N.A.
N.A.
52.7
40.9
43.9
P-Site Identity:
6.6
N.A.
N.A.
6.6
6.6
0
P-Site Similarity:
13.3
N.A.
N.A.
20
6.6
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
15
36
8
0
0
0
0
8
0
0
0
8
% A
% Cys:
0
0
0
0
0
22
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
15
0
8
8
36
0
15
8
15
0
36
0
0
% D
% Glu:
0
43
43
15
8
0
8
22
22
0
8
0
0
8
43
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
8
0
8
0
0
0
0
0
0
0
0
0
8
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
8
0
0
0
0
15
0
0
0
0
0
8
8
% I
% Lys:
0
8
8
0
8
8
15
0
0
36
43
8
15
0
8
% K
% Leu:
22
15
8
43
15
8
0
8
0
8
0
0
8
0
8
% L
% Met:
0
0
8
0
0
0
0
0
0
0
0
0
0
29
0
% M
% Asn:
0
0
0
8
0
0
8
0
29
15
15
0
8
8
8
% N
% Pro:
43
8
0
8
0
8
0
8
0
15
8
8
0
0
0
% P
% Gln:
8
0
0
0
8
0
8
0
8
0
8
0
0
8
0
% Q
% Arg:
0
0
0
15
0
29
8
8
15
0
0
15
8
8
0
% R
% Ser:
0
8
8
0
22
8
8
29
15
15
0
43
8
15
0
% S
% Thr:
0
0
0
0
0
0
8
15
0
8
0
22
0
15
0
% T
% Val:
0
8
0
0
0
0
8
0
0
0
0
8
8
0
22
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _